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MICROORGANISM PRODUCING 4-HYDROXYBUTYRATE AND A METHOD FOR PRODUCING 4-HYDROXYBUTYRATE IN ANAEROBIC CONDITION USING THE SAME
MICROORGANISM PRODUCING 4-HYDROXYBUTYRATE AND A METHOD FOR PRODUCING 4-HYDROXYBUTYRATE IN ANAEROBIC CONDITION USING THE SAME
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机译:产生4-羟基丁酸酯的微生物和在相同条件下厌氧条件下产生4-羟基丁酸酯的方法
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摘要
A genetically modified microorganism comprising a polynucleotide encoding α-ketoglutarate synthase or a mutant thereof, and a polynucleotide encoding pyruvate carboxylase or a mutant thereof; wherein the genetically modified microorganism has decreased malate quinone oxidoreductase activity and/or decreased phosphoenolpyruvate carboxykinase activity compared to an unmodified microorganism of the same type, and wherein the genetically modified microorganism produces 4-hydroxybutyrate.
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