NOVEL PHYTOSPHINGOSINE DERIVATIVES, AND A COSMETIC COMPOSITION COMPRISING THE SAME FOR PREVENTING AND AMELIORATING INFLAMMATORY SKIN DISEASES AND HYPERKERATOSIS DISEASES

摘要

A phytosphingosine derivatives of chemical formula IA or IB, and a cosmetic composition including the phytosphingosine derivative. The phytosphingosine derivatives are involved with transcription factors related to inflammation and hyperkeratotic diseases, the expression and the generation of inflammatory mediators, signal transduction mechanisms, and the expression and the activity of relevant enzymes and the like.