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High-yield transgenic mammalian expression system for generating virus-like particles
High-yield transgenic mammalian expression system for generating virus-like particles
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机译:用于产生病毒样颗粒的高产转基因哺乳动物表达系统
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摘要
Virus-like particles (VLPs) of mammalian-hosted viruses, such as SARS-CoV and influenza viruses, have been recombinantly produced from Vero cells. The VLPs closely emulate the exterior of authentic virus particles and are highly immunogenic. They can elicit not only humoral but also cellular immune responses in a mammal. Compositions and methods related to the VLPs are also described.
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