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siRNA Compositions and Methods for Inhibiting Gene Expression in Tumor Initiating Cells of breast Cancer
siRNA Compositions and Methods for Inhibiting Gene Expression in Tumor Initiating Cells of breast Cancer
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机译:siRNA组成和抑制乳腺癌肿瘤启动细胞中基因表达的方法
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摘要
Disclosed are methods and compositions for siRNA-mediated therapy of mammalian diseases. In particular, compositions and methods are disclosed for treatment of therapy-resistant human breast cancers. In exemplary embodiments, siRNA molecules are presented that effectively knock down gene expression of one or more polynucleotides in breast cancer tumor initiating cells.
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