Polypeptide, dimer or multimer, composition of matter, polynucleotide, expression vector, host cell, pharmaceutical composition, and methods of inhibiting unwanted angiogenesis in a mammal, treating angiogenesis in a patient, modulating angiogenesis in a mammal, to unite tumor growth distinguished by unwanted angiogenesis in a mammal, to treat cancer in a mammal, to modulate at least one of a vascular permeability or plasma leak in a mammal, and to treat disease

摘要

"Polypeptide, dimer or multimer, composition of matter, polynucleotide, expression vector, host cell, pharmacokinetic composition, and methods of inhibiting the angiography in an ani-genous annulus. , INHIBIT TUMOR GROWTH DISTINGUISHED BY UNGESTED ANGIOGENESIS IN A MAMMIFER, TREAT CANCER IN A MAMMER, MODULATE AT LEAST ONE VASCULAR PERMEABILITY OR PLASMA LEAK, AND DEAM. Peptides that bind to Ang-2 are disclosed. Also disclosed are peptibodies comprising peptides, methods of making such peptides and peptibodies, and treatment methods using such peptides and peptibodies.