Codon-optimized polynucleotides encoding human butyrylcholinesterase and plant expression systems therof

摘要

The present invention concerns the production of human butyrylcholinesterase (BuChE) in plants expressing a codon-optimized polynucleotides for the production thereof and use of the derived BuChE as effective counter measures against toxic agents such as pesticides, toxins, certain drugs and non-conventional warfare agents, as well as treatments for diseases and conditions associated with depressed cholinesterase levels.