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PHARMACEUTICAL OR DIETARY COMPOSITIONS BASED ON SHORT-CHAIN FATTY ACIDS AND COMPLEX SUGARS, FOR INTESTINAL DISORDERS

机译:基于短链脂肪酸和复合糖的药物或饮食组合物,用于肠道疾病

摘要

Pharmaceutical or dietary composition containing, as active ingredients, at least one short-chain fatty acid or salt, ester and/or amide thereof, in combination with a complex sugar and/or dietary fibre. The complex sugar and/or dietary fibre is selected from inulin, pectin, dextrin, maltodextrin or derivatives thereof and with one or more pharmacologically acceptable excipients. The composition has (a) a matrix consisting of lipophilic compounds with a melting point lower than 90° C. and optionally amphiphilic compounds in which the active ingredient are at least partially incorporated, (b) an amphiphilic matrix; and (c) an outer hydrophilic matrix in which the lipophilic matrix and the amphiphilic matrix are dispersed.
机译:包含至少一种短链脂肪酸或盐,其酯和/或酰胺以及复合糖和/或膳食纤维作为活性成分的药物或膳食组合物。复合糖和/或膳食纤维选自菊粉,果胶,糊精,麦芽糊精或其衍生物,以及一种或多种药理学可接受的赋形剂。该组合物具有(a)由熔点低于90℃的亲脂性化合物和任选地两亲化合物组成的基质,其中至少部分地掺入了活性成分;(b)两亲基质; (c)亲油性基质和两亲性基质分散的外部亲水性基质。

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