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Bacterium comprising a regulated rfaH nucleic acid

机译：包含受调控的 rfaH 核酸的细菌

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The present invention encompasses a recombinant bacterium comprising a regulated rfaH nucleic acid, as well as a vaccine comprising said recombinant bacterium. Other embodiments of the present invention encompass a recombinant bacterium comprising a regulated rfaH nucleic acid and a regulated rfc nucleic acid, while additional embodiments encompass a recombinant bacterium comprising a regulated rfaH nucleic acid and at least one nucleic acid encoding at least one exogenous antigen. 展开▼

机译：本发明包括包含调节的rfaH核酸的重组细菌，以及包含所述重组细菌的疫苗。本发明的其他实施方案包括包含调节的rfaH核酸和调节的rfc核酸的重组细菌，而另外的实施方案包括包含调节的rfaH核酸和至少一种编码至少一种外源抗原的核酸的重组细菌。展开▼

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公开/公告号US8889121B2

专利类型

公开/公告日2014-11-18

原文格式PDF

申请/专利权人 ROY CURTISS III;QINGKE KONG;
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申请/专利号US201113574718

发明设计人 ROY CURTISS III;QINGKE KONG;
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申请日2011-01-21

分类号A01N63;A61K39;A61K39/02;A61K39/112;C07K14/315;C07K14/255;C12N9/10;C12N1/36;A61K39/09;

国家 US

入库时间 2022-08-21 15:19:00

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1. 来自棒杆菌属细菌的新的启动子核酸、包含该启动子的表达盒和包含该表达盒的载体、包含该载体的宿主细胞和使用该细胞表达基因的方法 [P] . 中国专利： CN101087880B . 2011.05.11

2. 来自棒杆菌属细菌的新的启动子核酸、包含该启动子的表达盒和包含该表达盒的载体、包含该载体的宿主细胞和使用该细胞表达基因的方法 [P] . 中国专利： CN101712956B . 2011.12.21

3. BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID [P] . 欧洲知识产权局专利： EP2526185A4 . 2013-07-24

机译：含有规定的rfaH核酸的细菌

4. BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID [P] . 美国专利： US2013004537A1 . 2013-01-03

机译：含有规定的rfaH核酸的细菌

5. BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID [P] . 欧洲知识产权局专利： EP2526185A1 . 2012-11-28

机译：含有规定的rfaH核酸的细菌

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