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Inhibition of delta-6 desaturase for the treatment of cardiometabolic disease
Inhibition of delta-6 desaturase for the treatment of cardiometabolic disease
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机译:抑制delta-6去饱和酶治疗心脏代谢疾病
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摘要
Systems and methods for screening whether a candidate compound inhibits delta-6 desaturase activity are disclosed. Also disclosed is a transgenic mammal which overexpresses a gene encoding delta-6 desaturase and an animal model of a cardiometabolic disorder or disease that includes the transgenic mammal. A method of treating a cardiometabolic disorder or disease is also disclosed.
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