首页> 外国专利> Procedure for the synthesis of 3 - (2 - bromo - 4.5 - dimetoxifenil) propanenitrile, and application to the synthesis of Ivabradine and its Addition salts with a pharmaceutically acceptable acid

Procedure for the synthesis of 3 - (2 - bromo - 4.5 - dimetoxifenil) propanenitrile, and application to the synthesis of Ivabradine and its Addition salts with a pharmaceutically acceptable acid

机译:合成3-(2-溴-4.5-二甲氧西芬尼)丙烷腈的方法,以及与可药用酸合成伊伐布雷定及其加成盐的方法

摘要

Claim 1: procedure for Synthesis of the compound of formula (1), wherein the compound of formula (2) is subjected to the action of a base in the presence of acetonitrile in an organic solvent for the compound of formula (1).
机译:权利要求1:合成式(1)化合物的方法,其中使式(2)化合物在有机溶剂中在乙腈存在下,在式(1)化合物的有机溶剂中经受碱的作用。

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