rheumatoid arthritis treatment with the combination of laquinimod and methotrexate

摘要

a treatment of rheumatoid arthritis with the combination of laquinimod and methotrexarum mv. This invention provides a method of treating a person affected with rheumatoid arthritis which comprises periodically administering an amount of laquinimod or its pharmaceutically acceptable salt and an amount of methotrexate to an individual, wherein the amounts taken together are effective for treat the individual. This invention also provides laquinimod or its pharmaceutically acceptable salt for use in combination with methotrexate in the treatment of an individual afflicted with rheumatoid arthritis. This invention also provides a pharmaceutical composition comprising an amount of laquinimod or its pharmaceutically acceptable salt and an amount of methotrexate for use in treating an individual afflicted with rheumatoid arthritis.