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Composition and process for production of liquid form of administration on the basis of emulsified lipid systems, of the type emulsion, microemulsion and / or nanoemulsu00e3o containing praziquantel
Composition and process for production of liquid form of administration on the basis of emulsified lipid systems, of the type emulsion, microemulsion and / or nanoemulsu00e3o containing praziquantel
Composition and process for production of liquid form of administration on the basis of emulsified system, of the type emulsion, microemulsion and / or nanoemulsu00e3o containing praziquantel the invention patent refers to a liquid form of administration of praziquantel ( sym - 2ciclo - hexilcarbonil - 1 2,3,6,7,11b -, hexa - hydro - 4 - pirazino [2, 1] isoquinolin - 4 - one] contained in the interior of an oily phase.Emulsified within a phase with the aid of surfactants, which may be associated with CO surfactants and the direction of drug molecules to the parasite. The system may present as emulsified lipid emulsion, microemulsion and / or nanoemulsu00e3o, depending on the composition and method of manufacturing employees.These systems increase the amount of the drug soluble in an aqueous system up to more than 100 times, which potentially increases its oral absorption and enables its parenteral administration, changing thus bioavailability in relation to forms of administration di Sponu00edveis.
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