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A2 secretpha phosphatasease inhibitor (spla) and niacin drug compositions and method for treating cardiovascular disease and dyslipidemia
A2 secretpha phosphatasease inhibitor (spla) and niacin drug compositions and method for treating cardiovascular disease and dyslipidemia
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机译:A2分泌型磷酸酶抑制剂(Spla)和烟酸药物组合物以及治疗心血管疾病和血脂异常的方法
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摘要
Niacin drugs are frequently utilized as a therapeutic to treat CVD, increase HDL levels, and/or decrease TG levels. As disclosed herein, it has been found that administration of one or more sPLA2 inhibitors in combination with one or more niacin drugs unexpectedly results in a synergistic increase in HDL levels and a synergistic decrease in TG levels. Therefore, compositions, methods, and kits are provided for treating CVD, increasing HDL levels, decreasing TG levels, and improving HDL/LDL ratios.
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