Antibody that binds the ligands and calidina des arg10 - calidina bradykinin B1 Receptor Antibody; production method; Pharmaceutical composition containing Antibody method; use of the Antibody.

摘要

The disclosure provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The disclosure also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des-Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the disclosure to modulate Kallidin or des-Arg10-Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the disclosure . The disclosure further provides methods of making antibodies that specifically bind to des-Arg 9 - Bradykinin and des-Arg 10 -Kallidin-like peptide.