首页> 外国专利> 1-4-(5-cyanindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl) piperazine hydrochloride monohydrate in V crystalline form, processes for its preparation and medicament containing thereof

1-4-(5-cyanindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl) piperazine hydrochloride monohydrate in V crystalline form, processes for its preparation and medicament containing thereof

机译:V晶型的1- [4-(5-氰基吲哚-3-基)丁基] -4-(2-氨基甲酰基苯并呋喃-5-基)哌嗪盐酸盐一水合物,其制备方法和包含其的药物

摘要

In the present invention, there is disclosed 1-[4-(5-cyanindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine hydrochloride monohydrate in the V crystalline form characterized by data of X-ray diffraction. There are also disclosed processes for its preparation and medicament containing thereof and intended for the treatment or prevention of depressive disorders, anxiety, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypertension, cerebral disorders, chronic pain, acromegaly, hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.
机译:在本发明中,公开了特征为X-的数据的V结晶形式的1- [4-(5-氰基吲哚-3-基)丁基] -4-(2-氨基甲酰基苯并呋喃-5-基)哌嗪盐酸盐一水合物。射线衍射。还公开了其制备方法和包含其的药物,所述药物旨在用于治疗或预防抑郁症,焦虑症,躁郁症,躁狂症,痴呆症,与物质有关的病症,性功能障碍,进食障碍,肥胖症,纤维肌痛,睡眠障碍,精神疾病,脑梗塞,紧张,用于治疗高血压,脑部疾病,慢性疼痛,肢端肥大症,性腺机能减退,继发性闭经,经前综合症和不希望的产褥期泌乳。

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