PHARMACEUTICAL COMPOSITION, INTENDED FOR THE TREATMENT OF DISEASES OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM OF VASCULAR, TRAUMATIC, TOXIC, HYPOXIC AND AUTOMOMMUNE

摘要

The invention relates to a pharmaceutical composition intended for the treatment of diseases of the central and peripheral nervous system of the vascular, traumatic, toxic, hypoxic and autoimmune genesis, made in the form of a solution for parenteral, intranasal and subconjunctival administration, containing as an active ingredient a biologically active protein-polypeptide complex concentration of 0.01-2.0 mg / ml, which has a tissue-specific reparative effect on the nervous tissue, derived from emb ronalnogo brain agricultural hoofed animals with a period of gestation from the middle of the first to the middle of the last third of pregnancy, including negatively charged weakly acidic, neutral proteins and polypeptides related to growth factors, differentiation, signaling molecules that determine its biological and pharmacological activity, with molecular weights from 5 to 200 kDa, and not less than 80% of the total mass of the protein has a molecular mass of from 10 to 120 kDa, characterized by the presence of a peak at a wavelength of 274-284 nm in the visible UV region and spectrum and the presence of bands at pI values ranging from 4.2 to 8.4 with isoelectric focusing in a 5% polyacrylamide gel, and a pharmaceutically acceptable diluent.