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C-kit kinase inhibitors for use in treating mastocytosis and gastrointestinal stromal tumors and compositions comprising them
C-kit kinase inhibitors for use in treating mastocytosis and gastrointestinal stromal tumors and compositions comprising them
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机译:用于治疗肥大细胞增多症和胃肠道间质瘤的C-kit激酶抑制剂及其组合物
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摘要
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a ompound of the present invention: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
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