首页> 外国专利> 2,5-disubstituted imidazo2,1-b1,3,4thiadiazole derivatives, process for their preparation and pharmaceutical compositions comprising them

2,5-disubstituted imidazo2,1-b1,3,4thiadiazole derivatives, process for their preparation and pharmaceutical compositions comprising them

机译:2,5-二取代的咪唑并[2,1-b] [1,3,4]噻二唑衍生物,其制备方法和包含它们的药物组合物

摘要

There is provided compounds of formula (I): wherein R1, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K) is desired and/or required, and particularly in the treatment of cancer.
机译:提供了式(I)的化合物:其中R 1,R 2和R 3具有说明书中给出的含义,以及其药学上可接受的酯,酰胺,溶剂化物或盐,这些化合物可用于治疗抑制Aβ的疾病。蛋白或脂质激酶(例如PI3-K,特别是I类PI3K)是期望和/或需要的,尤其是在癌症的治疗中。

著录项

  • 公开/公告号IL215158A

    专利类型

  • 公开/公告日2015-07-30

    原文格式PDF

  • 申请/专利号IL20110215158

  • 发明设计人

    申请日2011-09-15

  • 分类号A61K;A61P;C07D;

  • 国家 IL

  • 入库时间 2022-08-21 15:15:22

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