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Nanoparticles process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds

机译:纳米颗粒的制备方法及其用作疏水分子两性的载体在医学领域中的应用,包括癌症治疗和食品相关化合物

摘要

The present invention regards nanoparticles comprising a sterol and a component derived from Quillaja saponaria Molina selected from quillaja acid and quillaja saponin which nanoparticles do not comprise a phospholipid. It also relates to a composition comprising the nanoparticles and the use thereof as adjuvant especially in vaccines as carriers for amphipathic or hydrophobic molecules and as agents for treatment of cancer. Further it regards a method for producing the phospholipid free nanoparticles a method for the treatment of cancer and a method for assessing the applicability of the cancer treating method.
机译:本发明涉及包含固醇和衍生自Quillaja saponaria Molina的组分的纳米颗粒,所述组分选自奎拉雅酸和奎拉雅皂苷,其中所述纳米颗粒不包含磷脂。它还涉及包含纳米颗粒的组合物及其作为佐剂的用途,特别是在疫苗中作为两亲或疏水分子的载体以及作为癌症治疗剂的用途。此外,本发明涉及用于生产无磷脂纳米颗粒的方法,用于治疗癌症的方法和用于评估该癌症治疗方法的适用性的方法。

著录项

  • 公开/公告号IN2014DN03485A

    专利类型

  • 公开/公告日2015-06-05

    原文格式PDF

  • 申请/专利权人 MOREINX AB;

    申请/专利号IN3485/DELNP/2014

  • 发明设计人 HU KAFEI;MOREIN BROR;BERENJIAN SAIDEH;

    申请日2014-04-30

  • 分类号A61K36/00;A61K31/015;

  • 国家 IN

  • 入库时间 2022-08-21 15:14:44

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