首页> 外国专利> NANOPARTICLES, PROCESS FOR PREPARATION AND USE THEREOF AS CARRIER FOR AMPHIPATIC OF HYDROPHOBIC MOLECULES IN FIELDS OF MEDICINE INCLUDING CANCER TREATMENT AND FOOD RELATED COMPOUNDS

NANOPARTICLES, PROCESS FOR PREPARATION AND USE THEREOF AS CARRIER FOR AMPHIPATIC OF HYDROPHOBIC MOLECULES IN FIELDS OF MEDICINE INCLUDING CANCER TREATMENT AND FOOD RELATED COMPOUNDS

机译:纳米颗粒,制备方法及其在包括癌症治疗和食品相关化合物在内的医学领域中用作疏水性两性分子载体的方法

摘要

The present invention regards nanoparticles comprising a sterol and a component derived from Quillaja saponaria Molina selected from quillaja acid and quillaja saponin, which nanoparticles do not comprise a phospholipid. It also relates to a composition comprising the nanoparticles, and the use thereof as adjuvant, especially in vaccines, as carriers for amphipathic or hydrophobic molecules and as agents for treatment of cancer. Further, it regards a method for producing the phospholipid-free nanoparticles, a method for the treatment of cancer and a method for assessing the applicability of the cancer treating method.
机译:本发明涉及包含固醇和衍生自Quillaja saponaria Molina的组分的纳米颗粒,该组分选自奎拉雅酸和奎拉雅皂苷,该纳米颗粒不包含磷脂。它还涉及包含纳米颗粒的组合物,及其在佐剂中的用途,特别是在疫苗中,作为两亲或疏水分子的载体以及作为癌症治疗剂的用途。此外,其涉及用于生产无磷脂纳米颗粒的方法,用于治疗癌症的方法以及用于评估该癌症治疗方法的适用性的方法。

著录项

  • 公开/公告号TR201808733T4

    专利类型

  • 公开/公告日2018-07-23

    原文格式PDF

  • 申请/专利权人 MX ADJUVAC AB;

    申请/专利号TR20180008733T

  • 发明设计人 BROR MOREIN;SAIDEH BERENJIAN;KEFEI HU;

    申请日2012-10-01

  • 分类号A61K31/015;A61K36;

  • 国家 TR

  • 入库时间 2022-08-21 12:49:54

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