Method for screening anticancer drugs and anticancer drug that induces cell death and uses substance that increases granzyme m activity as active ingredient

摘要

pThe purpose of the present invention is to provide a method for screening anticancer drugs that use novel treatment mechanisms and an anticancer drug that induces cell death and uses a substance that increases the activity of granzyme M as an active ingredient. This method for screening anticancer drugs comprises: a step for administering test substances to cancer cells; a step for detecting the activity of granzyme M in which cancer cells are expressed and selecting test substances for which an increase in activity has been verified; and/or a step for detecting the presence or absence of cancer cell death induced by the activation of granzyme M in which cancer cells are expressed and selecting test substances for which cell death has been verified./p