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METHOD FOR SCREENING ANTICANCER DRUGS, AND ANTICANCER DRUG THAT INDUCES CELL DEATH AND USES SUBSTANCE THAT INCREASES GRANZYME M ACTIVITY AS ACTIVE INGREDIENT
METHOD FOR SCREENING ANTICANCER DRUGS, AND ANTICANCER DRUG THAT INDUCES CELL DEATH AND USES SUBSTANCE THAT INCREASES GRANZYME M ACTIVITY AS ACTIVE INGREDIENT
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机译:筛选抗癌药的方法,以及诱导细胞死亡并使用增加粒状酶M活性的物质作为活性成分的抗癌药
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摘要
The purpose of the present invention is to provide a method for screening anticancer drugs that use novel treatment mechanisms, and an anticancer drug that induces cell death and uses a substance that increases the activity of granzyme M as an active ingredient. This method for screening anticancer drugs comprises: a step for administering test substances to cancer cells; a step for detecting the activity of granzyme M in which cancer cells are expressed, and selecting test substances for which an increase in activity has been verified; and/or a step for detecting the presence or absence of cancer cell death induced by the activation of granzyme M in which cancer cells are expressed, and selecting test substances for which cell death has been verified.
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