‘’a green process for synthesis of ß-hydroxy aryl ethers in presence of transition metal nanoparticles’’

摘要

The present invention provides a widely applicable, efficient and green chemical process for the synthesis of ß-hydroxy aryl ethers by the reaction of phenol with epoxide in the presence of metal nanoparticles as catalysts. The process of the present invention, which involves metal nanoparticle catalysed epoxide ring opening by phenols can be extended to a broad range of drugs with varied applications like treatment of cold and cough, as muscle relaxants, as cardiovascular drugs.