TERT BUTYL N- 2- {4- 6- AMINO 5 -(2, 4- DIFLUOROBENZOYL)- 2- OXOPYRIDIN -1(2H-) YL 3 ,5- DIFLUOROPHENYL}ETHYL- L- ALANINATE OR A SALT, HYDRATE OR SOLVATE THEREOF

摘要

The present invention provides a compound which is: tert butyl N- [2 -{4- [6- amino -5- (2, 4- difluorobenzoyl) -2- oxopyridin- 1(2H)- yl] -3, 5- difluorophenyl}ethyl)- L- alaninate or a salt, hydrate or solvate thereof. The present invention also provides a pharmaceutical composition comprising the compound together with one or more pharmaceutically acceptable carriers and/or excipients. The compound and composition are useful for inhibiting the activity of a p38 MAP kinase enzyme. As such they may be used in the treatment of a autoimmune or inflammatory disease , or a cell proliferative disease. In addition the invention provides an acid produced by hydrolysis of the ester group of the compound of the invention. The acid is N- [2- {4- [6 -amino- 5- (2, 4- difluorobenzoyl)- 2 - oxopyridin- 1(2H)- yl]- 3 ,5- difluorophenyl}ethyl) -L- alanine.