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Purification process for rivaroxaban

机译:利伐沙班的纯化工艺

摘要

This invention mainly relates to a process for the purification of rivaroxaban and its pharmaceutically accepted salts, wherein the crude rivaroxaban treated with an acid optionally, in presence of solvent to form clear solution which further precipitates out the pure rivaroxaban or its pharmaceutically accepted salt by adding anti-solvent. The obtained rivaroxaban having the desired purity with quality by avoiding any further purification
机译:本发明主要涉及利伐沙班及其药学上可接受的盐的纯化方法,其中在溶剂存在下任选地用酸处理过的利伐沙班粗品以形成澄清溶液,其通过加入进一步沉淀出纯利伐沙班或其药学上可接受的盐。反溶剂。通过避免进一步纯化,所获得的利伐沙班具有所需的纯度和质量

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