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DIFLUORO-HEXAHYDRO-CYCLOPENTAOXAZINYLS AND DIFLUORO-HEXAHYDRO-BEN ZOOXAZINYLS AS BACE1 INHIBITORS.
DIFLUORO-HEXAHYDRO-CYCLOPENTAOXAZINYLS AND DIFLUORO-HEXAHYDRO-BEN ZOOXAZINYLS AS BACE1 INHIBITORS.
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机译:作为BACE1抑制剂的二氟六环杂环苯并恶唑啉和二氟六氮杂苯并二恶唑。
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摘要
The present invention provides difluoro-cyclopentaoxazinyls and difluoroenzooxazinyls of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
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