首页>
外国专利>
DIPHENYLSULFIDDERIVATE UND ARZNEIMITTEL, WELCHE DIESE ALS WIRKSTOFF ENTHALTEN
DIPHENYLSULFIDDERIVATE UND ARZNEIMITTEL, WELCHE DIESE ALS WIRKSTOFF ENTHALTEN
展开▼
机译:包含二苯硫醚衍生物和药用产品的活性物质
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are diphenyl sulfide derivatives which have excellent S1P3 antagonistic activity and are useful as drugs. Intensive studies have been made for the purpose of creating a compound having S1P3 antagonistic activity. As a result of the intensive studies, it has been found that diphenyl sulfide derivatives representedby general formula (1) have excellent S1P3 antagonistic activity. In general formula (1), R 1 is a hydrogen atom or the like; R 2 is an optionally substituted alkyl group having 1 to 6 carbon atoms, or the like; X is a methylene group which may be substituted with one or two fluorine atoms, or the like; Y is a hydrogen atom or the like; and Z is a halogen atom.
展开▼
机译:提供具有优异的S1P3拮抗活性并且可用作药物的二苯硫醚衍生物。为了产生具有S1P3拮抗活性的化合物,已经进行了深入的研究。作为深入研究的结果,发现由通式(1)表示的二苯硫醚衍生物具有优异的S1P3拮抗活性。通式(1)中,R 1为氢原子等。 R 2为碳数1〜6的可被取代的烷基等。 X为可被一个或两个氟原子等取代的亚甲基; Y为氢原子等。 Z为卤原子。
展开▼