Long-acting and controlled release formulation containing a dopamine receptor agonist and method of preparation thereof

摘要

Preparation of controlled release and prolonged action for the treatment of Parkinson's disease, which comprises rotigotine or a pharmaceutically acceptable salt thereof, and poly (lactide-glycolide), wherein the content of rotigotine or salt thereof in the preparation Controlled release is 10-30% by weight, and the content of poly (lactide-glycolide) is 70-90% by weight, where the rotigotine or salt thereof in the poly (lactidoglycolide) is present in the solid solution status.