Treatment of pituitary corticotropic tumors using R-roscovitine

摘要

A composition comprising olomucine or R-roscovitine or salts thereof for use as a medicament for administration, in a therapeutically effective amount, to a mammalian subject in need of treating a pituitary corticotropic tumor, suppressing ACTH and / or levels of corticosterone in an ACTH-secreting pituitary adenoma, inhibit the growth of an ACTH-secreting pituitary adenoma, or treat Cushing's disease to treat the pituitary corticosteroid tumor, suppress ACTH and / or corticosterone levels in an ACTH-secreting pituitary adenoma, inhibit the growth of an ACTH-secreting pituitary adenoma or treat Cushing's disease.