PHARMACEUTICAL COMPOSITION COMPRISING A SOLID DISPERSION WITH A POLYMER MATRIX CONTAINING A CONTINUOUS POLYDEXTROSE PHASE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE

摘要

the present invention relates to a solid pharmaceutical compositionsolid dispersion comprising an active ingredient and having at least one of apharmaceutically acceptable polymer matrix, characterized in that saidpharmaceutically acceptable polymer matrix comprises (i) polydextrosein order to promote the dissolution of the composition in an aqueous medium, in the forma continuous phase of polydextrose, mixed with (ii) at least onethe polymer other than polydextrose, in the form of a continuous phase of thethe polymer, the proportion of polydextrose being at least 20% by weight.the proportion of at least one polymer other than polydextrose is inless than 20% by weight, relative to the total weight of the polymer matrixpharmaceutically acceptable.