首页> 外国专利> Pharmaceutical compositions containing a polymer with a matrix comprising a continuous phase of a solid dispersion continuous polydextrose phase and polydextrose other polymers

Pharmaceutical compositions containing a polymer with a matrix comprising a continuous phase of a solid dispersion continuous polydextrose phase and polydextrose other polymers

机译:药物组合物,其包含具有基质的聚合物,所述基质包括固体分散体的连续相,连续聚葡萄糖相和聚葡萄糖其他聚合物

摘要

The present invention relates to a solid pharmaceutical composition comprising a solid dispersion comprising a polymeric matrix and a pharmaceutically acceptable active ingredient at least one. The present invention, in the form of (ii) a continuous phase and polydextrose that for polymer matrix pharmaceutically acceptable to promote disintegration of the composition in (i) an aqueous medium, in the form of a continuous polydextrose phase one comprises at least one polymer polydextrose non Thus, the polymer matrix of a pharmaceutically acceptable, polydextrose is a concentration of 20wt% at least, the at least one polymer of polydextrose than and characterized by a concentration of 20wt% at least.
机译:本发明涉及包含固体分散体的固体药物组合物,所述固体分散体包含聚合物基质和至少一种药学上可接受的活性成分。 (ii)连续相和聚右旋糖的形式,其对于药学上可接受的聚合物基质是药学上可接受的,以促进组合物在(i)水性介质中的崩解,以连续聚右旋糖相的形式,本发明包含至少一种聚合物因此,药学上可接受的聚葡萄糖的聚合物基质的浓度至少为20wt%,至少一种聚葡萄糖的聚合物的浓度为至少20wt%,并且其特征在于浓度至少为20wt%。

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