BENZIMIDAZOLE-TYPE COMPOUND EXHIBITING ANTI-TUMOR ACTIVITY, PREPARATION METHOD AND USE THEREOF

摘要

The present invention discloses, as shown in Formula (I), a benzimidazole-type compound exhibiting anti-tumor activity, and a preparation method and use thereof. Wherein, R¹，R²，R³，R⁴，and R⁵ are as described in the description, and the compound and pharmaceutically acceptable salt of the present invention maintain, in regard to an Hh signaling pathway, activation of an inhibitory effect related to tumor cancer cell growth comparable to or superior to that of GDC-0449, thus providing a new option for tumor-related treatment.