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PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RHEUMATOID ARTHRITIS, COMPRISING PEPTIDE AS ACTIVE INGREDIENT
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RHEUMATOID ARTHRITIS, COMPRISING PEPTIDE AS ACTIVE INGREDIENT
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机译:用于预防或治疗类风湿关节炎的药物组合物,其包含肽作为活性成分
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摘要
The present invention relates to a pharmaceutical composition for preventing or treating rheumatoid arthritis, comprising, as an active ingredient, a peptide consisting of an amino acid sequence having SEQ ID NO: 1. The pharmaceutical composition according to the present invention has an advantageous effect of inhibiting the generation and activation of osteoclasts, as well as inhibiting the differentiation and activation of Th17 cells and TFH cells, which are important in the etiological process of rheumatoid arthritis, and is thus expected to be applicable to the fundamental treatment of rheumatoid arthritis.
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机译:本发明涉及用于预防或治疗类风湿性关节炎的药物组合物,其包含作为有效成分的由具有SEQ ID NO:1的氨基酸序列组成的肽。抑制破骨细胞的产生和活化,以及抑制Th17细胞和T FH Sub>细胞的分化和活化,这在类风湿性关节炎的病因学过程中很重要,因此有望应用于类风湿关节炎的根本治疗。
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