首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BEHCET'S DISEASE AND RHEUMATOID ARTHRITIS, CONTAINING PEPTIDE OR MIXTURE THEREOF AS ACTIVE INGREDIENT

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BEHCET'S DISEASE AND RHEUMATOID ARTHRITIS, CONTAINING PEPTIDE OR MIXTURE THEREOF AS ACTIVE INGREDIENT

机译:用于预防或治疗Behcet病和类风湿性关节炎的药物组合物,含有肽或其混合物作为活性成分

摘要

The present invention relates to a composition for preventing or treating Behcet's disease and rheumatoid arthritis, the composition containing a peptide or a mixture thereof as an active ingredient. More specifically, an intraperitoneal injection or application of P1 to P5 peptides or a mixture thereof as a skin external preparation to a mouse animal model having Behcet's disease caused by autoimmune reaction was found to ameliorate skin ulcers and skin inflammation in the Behcet's disease mouse model, and an arthritis amelioration effect on a rheumatoid arthritis animal model was also observed. Accordingly, the composition containing P1 to P5 peptides or mixtures thereof as active ingredients can be provided as medicine for Behcet's disease and rheumatoid arthritis.
机译:本发明涉及用于预防或治疗Behcet疾病和类风湿性关节炎的组合物,该组合物含有肽或其混合物作为活性成分。更具体地,发现P1至P5肽或其混合物作为皮肤外部制剂的腹膜内注射或施用于由自身免疫反应引起的小鼠动物模型中的皮肤外部制剂,以改善Behcet疾病小鼠模型中的皮肤溃疡和皮肤炎症,还观察到对类风湿性关节炎动物模型的关节炎改善效果。因此,可以提供含有P1至P5肽或其混合物作为活性成分的组合物作为Behcet病和类风湿性关节炎的药物。

著录项

  • 公开/公告号WO2021112614A1

    专利类型

  • 公开/公告日2021-06-10

    原文格式PDF

  • 申请/专利号WO2020KR17627

  • 发明设计人 SOHN SEONGHYANG;

    申请日2020-12-04

  • 分类号A61K38/10;A61K38/08;A61P19/02;A61P29;A61P17/06;A61P1;A61P11/06;A61K38/17;A61K35/583;A61P37;

  • 国家 KR

  • 入库时间 2022-08-24 19:17:25

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