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ARTEMISININ-BASED COMBINATION THERAPY FOR TREATING VIRAL MEDIATED DISEASE

机译:基于青蒿素的联合治疗病毒介导的疾病

摘要

The present invention describes a method of treating individuals suffering from microbial infections, including a viral infection such as Dengue Fever, using an improved Artemisinin Combination Therapy (ACT), known as Tri-ACT. The improved ACT therapy includes administering a combination of three drugs. In one embodiment of the present invention, the method includes administering to an individual a first composition comprising a therapeutically effective amount of an artemether spray sublingually. The individual is then administered a second composition, a therapeutically effective amount of artesunate. A third composition, an effective amount of berberine, or its pharmaceutically acceptable derivatives or salts is then administered to the individual.
机译:本发明描述了一种使用称为Tri-ACT的改良青蒿素联合疗法(ACT)来治疗患有微生物感染的个体的方法,所述微生物感染包括病毒感染,例如登革热。改进的ACT疗法包括施用三种药物的组合。在本发明的一个实施方案中,该方法包括向个体舌下施用包含治疗有效量的蒿甲醚喷雾剂的第一组合物。然后给个体施用第二组合物,即治疗有效量的青蒿琥酯。然后将第三种组合物,有效量的小ber碱或其药学上可接受的衍生物或盐施用于个体。

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