Systems and methods for assembly of metagenomic sequences are described herein. In one embodiment, a plurality of metagenomic sequences is represented in three dimensional space to obtain a plurality of sequence vectors. Based on plurality of the sequence vectors, a cuboid having a plurality of grids is defined in the three dimensional space such that it encompasses the plurality of metagenomic sequences. Further, the plurality of metagenomic sequences is assembled into one or more contigs based on traversal of the plurality of grids. In one implementation, the one or more contigs are assembled such that a contig includes metagenomic sequences probably originating from the same genome.
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