METHOD FOR EVALUATING RENIN ACTIVITY, METHOD FOR TESTING MORBIDITY POTENTIAL FOR PRIMARY ALDOSTERONISM, AND KIT USING SAME

摘要

The purpose of the present invention is to provide a method for evaluating renin activity and a method for testing morbidity potential for primary aldosteronism. In the present invention, the relationship between the amount of X (angiotensinogen having angiotensin I: intact AGT) and the amount of Y (angiotensinogen from which angiotensin I is separated: des-AngI AGT) for a subject is calculated, and renin activity in the subject is evaluated by comparing the calculated relationship with a reference for evaluation. The reference for evaluation is a correlation of the relationship between the amount of X and the amount of Y in a standard specimen and the renin activity of the standard specimen. The renin activity indicates a correlation with morbidity of primary aldosteronism; therefore, by evaluating renin activity on the basis of the aforementioned relationship, it is possible to test the morbidity potential for primary aldosteronism.