首页> 外国专利> Sensor for analysis of cortisol, method for analysis of cortisol, reagent for stress evaluation, method for stress evaluation, test reagent for cortisol related disease, and method for testing morbidity of cortisol related disease

Sensor for analysis of cortisol, method for analysis of cortisol, reagent for stress evaluation, method for stress evaluation, test reagent for cortisol related disease, and method for testing morbidity of cortisol related disease

机译:皮质醇分析用传感器,皮质醇分析方法,压力评估试剂,压力评估方法,皮质醇相关疾病的测试试剂以及皮质醇相关疾病的发病率测试方法

摘要

A novel sensor for analysis of cortisol, a method for analysis of cortisol, a method for evaluating stress, a method for evaluating stress, a test reagent for cortisol related diseases, and a method for testing the morbidity of cortisol related diseases are provided. The sensor for analysis of cortisol according to the present invention comprises the group consisting of (I), (II) and (III) comprising a binding region (A) binding to a target and a G forming region (D) forming a G-quartet structure. Comprising at least one nucleic acid molecule selected; The target is cortisol, In the absence of the target, the G-forming region (D) is inactivated since the formation of the G-quartet structure is inhibited. In the presence of the target, the G formation region (D) forms a G-quartet structure to be an active type.
机译:提供了一种新型的皮质醇分析传感器,一种皮质醇分析方法,一种评估压力的方法,一种评估应力的方法,一种用于皮质醇相关疾病的测试试剂以及一种用于检测皮质醇相关疾病的发病率的方法。根据本发明的用于分析皮质醇的传感器包括由(I),(II)和(III)组成的组,所述组包括结合至靶标的结合区(A)和形成G-的G形成区(D)。四重奏结构。包含至少一种选择的核酸分子;目标是皮质醇,在不存在目标的情况下,由于抑制了G四方结构的形成,因此使G形成区域(D)失活。在靶的存在下,G形成区域(D)将G四方结构形成为活性类型。

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