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RECURRENT SPOP MUTATIONS IN PROSTATE CANCER
RECURRENT SPOP MUTATIONS IN PROSTATE CANCER
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机译:前列腺癌的复发性SPOP突变
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摘要
The invention relates generally to new prostate cancer markers, and particularly to a class of cancer marked by the presence of missense mutations in SPOP, an E3 ubiquitin ligase component. The invention provides methods and materials for detecting and diagnosing prostate cancer by detecting these mutations and may be useful in predicting disease progression and response to therapy.
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