COMPOUNDS INHIBITING EUKARYOTIC ELONGATION FACTOR 2 KINASE ACTIVITY

摘要

Eukaryotic elongation factor 2 kinase inhibitors of the formula (I) where R₁, R₂, R_3a, R_3b, R_4a, R_4b, R_5a, R_5b, R_6a, R_6b, R₇ and x are as defined in the specification, pharmaceutical compositions and formulations including compounds of the foregoing formula, and methods of preventing, ameliorating or treating indications, conditions, disorders or syndromes associated with elongation factor 2 phosphorylation.