COMPOSITION FOR PREDICTING RISK OF THIOPURINE-INDUCED LEUKOPENIA, CONTAINING SINGLE NUCLEOTIDE POLYMORPHISM MARKER WITHIN NUDT15 GENE

摘要

The present invention relates to a composition for predicting the risk of thiopurine-induced leukopenia, containing a single nucleotide polymorphism marker within NUDT15 gene, and specifically, to: a composition for predicting the risk of thiopurine-induced leukopenia in Crohn's disease, ulcerative colitis, leukemia or transplant patients, containing a single nucleotide polymorphism marker within NUDT15 gene; a kit for predicting the risk; and a method for predicting the risk. According to the present invention, a patient having high sensitivity to leukopenia, which occurs during thiopurine therapy, in Crohn's disease, ulcerative colitis, leukemia or transplant patients can be rapidly classified early on, and thus patient-customized therapy can be efficiently carried out.