Composition for predicting the risk of thiopurine-induced leukopenia, comprising a single nucleotide polymorphism marker in NUDT15 gene

摘要

The present invention relates to a composition for predicting the onset risk of thiopurine-induced leukopenia comprising a single nucleotide polymorphism marker in the NUDT15 gene, and specifically includes a single nucleotide polymorphism marker in the NUDT15 gene. The present invention relates to a risk prediction composition, risk prediction kit and risk prediction method for thiopurine-induced leukopenia in patients with Crohn's disease, ulcerative colitis, leukemia or organ transplantation. According to the present invention, patients with Crohn's disease, ulcerative colitis, leukemia or organ transplantation can be quickly and quickly classified into patients who are highly sensitive to leukopenia occurring during the thiopurine treatment process. Can perform patient customized treatment efficiently.