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Methods for reverting methylation by targeting DNMT3A and DNMT3B
Methods for reverting methylation by targeting DNMT3A and DNMT3B
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机译:通过靶向DNMT3A和DNMT3B还原甲基化的方法
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摘要
Methods for restoring a desired pattern of DNA methylation, inducing re-expression of methylation-silenced tumor suppressor genes (TSGs), and/or inhibiting tumorigenicity both in vitro and in vivo in a subject in need thereof by administering an effective amount of one or more miR-29s sufficient to target one or more of DNMT3A and DNMT3B are disclosed.
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