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AN EXPRESSION VECTOR COMPRISING A POLYNUCLEOTIDE ENCODING A MODIFIED GLUTAMINE SYNTHETASE AND A METHOD FOR PREPARING A TARGET PROTEIN EMPLOYING THE SAME
AN EXPRESSION VECTOR COMPRISING A POLYNUCLEOTIDE ENCODING A MODIFIED GLUTAMINE SYNTHETASE AND A METHOD FOR PREPARING A TARGET PROTEIN EMPLOYING THE SAME
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机译:包含编码修饰的谷氨酰胺合成酶的多核苷酸的表达载体和制备使用相同靶蛋白的方法
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摘要
The present invention relates to a vector comprising a polynucleotide encoding a modified glutamine synthetase (GS), and a method for preparing a target protein employing the same. More particulary, the present invention relates to a modified GS having an increased sensitivity to a glutamine synthetase (GS) inhibitor, a polynucleotide encoding the modified GS, a vector comprising the polynucleotide, a transformat comprising the vector, and a method for preparing a target protein using the transformat.
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