首页> 外国专利> Expression Vector Comprising a Polynucleotide Encoding a Modified Glutamine Synthetase and a Method for Preparing a Target Protein Employing the Same

Expression Vector Comprising a Polynucleotide Encoding a Modified Glutamine Synthetase and a Method for Preparing a Target Protein Employing the Same

机译:包含编码修饰的谷氨酰胺合成酶的多核苷酸的表达载体和使用其的靶蛋白的制备方法

摘要

The present invention relates to a vector comprising a polynucleotide encoding a modified glutamine synthetase (GS), and a method for preparing a target protein employing the same. More particulary, the present invention relates to a modified GS having an increased sensitivity to a glutamine synthetase (GS) inhibitor, a polynucleotide encoding the modified GS, a vector comprising the polynucleotide, a transformat comprising the vector, and a method for preparing a target protein using the transformat.
机译:本发明涉及包含编码修饰的谷氨酰胺合成酶(GS)的多核苷酸的载体,以及使用该载体制备靶蛋白的方法。更具体地,本发明涉及对谷氨酰胺合成酶(GS)抑制剂具有增加的敏感性的修饰的GS,编码该修饰的GS的多核苷酸,包含该多核苷酸的载体,包含该载体的转化子以及制备靶标的方法。蛋白质使用transformat。

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