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MATERIALS AND METHODS FOR DIAGNOSIS OF PERI-IMPLANT BONE AND JOINT INFECTIONS USING PROPHENOLOXIDASE PATHWAY
MATERIALS AND METHODS FOR DIAGNOSIS OF PERI-IMPLANT BONE AND JOINT INFECTIONS USING PROPHENOLOXIDASE PATHWAY
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机译:利用苯酚过氧化物酶途径诊断种植体周围骨和关节感染的材料和方法
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摘要
Diagnostic assays and related systems, test samples and methods are described for detection of infection following implantation of a prosthetic material or device on and/or into bones and joints. A combination of at least two biomarkers is used, one specific to the pathogenic microbe and the other specific to the destruction of peri-implant tissues. The biomarkers are detectable in the peripheral blood, urine, fluid or tissue samples drawn from a peri-implant environment. They can also be detected with a blood or urine test that is highly sensitive for detecting specific structural microbial molecules and peri-implant tissue components.
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