Animal model for Parkes-Weber syndrome

摘要

A non-human animal mammalian model for Parkes-Weber syndrome, wherein an animal has an arteriovenous fistula and a venous ligature in at least one of the limbs, is provided. The invention also relates to a method for preparing the model. The desired model reflects the pathophysiological characteristics of PW syndrome and can be used in studies on PW syndrome, including etiology of the syndrome. The animal model can also be used for screening a material for vascular use and for screening a preventive and/or therapeutic agent for Parkes-Weber syndrome.