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DISEASE MODEL ANIMALS OF METABOLIC SYNDROME AND A METHOD OF SCREENING PREVENTIVE AND THERAPEUTIC AGENTS FOR METABOLIC SYNDROME USING THE SAME
DISEASE MODEL ANIMALS OF METABOLIC SYNDROME AND A METHOD OF SCREENING PREVENTIVE AND THERAPEUTIC AGENTS FOR METABOLIC SYNDROME USING THE SAME
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机译:代谢综合征的疾病模型动物及使用该方法筛选代谢综合征的预防和治疗剂的方法
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摘要
The object of the invention is to provide animal model of disorder and method of screening an agent for preventing or treating Metabolic Syndrome by using the animal model, wherein said animal model is used as experimental material which is essential to detailed analysis of component and pathologic condition of Metabolic Syndrome and to development of the method for treating and the agent for preventing and treating the Metabolic Syndrome.;The above object is achieved by the non-human mammal model of disorders, whose TBP-2 gene is functionally deficient on chromosome, wherein the disorders are caused by impaired fatty acid utilization, and a method of screening an agent for preventing or treating Metabolic syndrome comprising; administering a test article to the non-human mammal whose TBP-2 gene is functionally deficient on chromosome.
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