TREATING AGENT CONTAINING INTERFERON-BETA INTRODUCED HUMAN BONE MARROW-DERIVED IFNamp;beta;-hBM-MSCs

摘要

The present invention relates to a composition containing IFNβ-hBM mesenchymal stem cells (MSCs) to which IFN-β gene is introduced as an active ingredient for preventing or treating multiple sclerosis or encephalomyelitis; and to a method for producing the same. More specifically, the IFNβ-hBM-MSCs of the present invention have immunomodulatory functions of reducing Th1 cytokine in blood plasma and increasing Th2 cytokine in blood plasma; prevent demyelination of nerve cells; have a neuroprotective effect; and inhibit inflammatory infiltration or inhibit permeability of a blood brain barrier (BBB). Therefore, the composition can be used for preventing and treating multiple sclerosis and encephalomyelitis.;COPYRIGHT KIPO 2015