首页> 外国专利> Undifferentiated mesenchymal stem cells with higher self-renewal and osteogenic potential and method for preparing the same

Undifferentiated mesenchymal stem cells with higher self-renewal and osteogenic potential and method for preparing the same

机译:具有较高自我更新和成骨潜能的未分化间充质干细胞及其制备方法

摘要

the present invention is to accelerate cell proliferation and self-renewal ability and increased bone cells, multipotent relates to the undifferentiated mesenchymal stem cells and their preparation have , more specifically , to a mesenchymal stem cell and a method for producing separated by culture in a culture medium containing human umbilical cord blood serum . In addition, the present invention relates to a bone differentiation-inducing method using this composition for bone and differentiation induction for differentiation of mesenchymal stem cells comprising as active ingredient human cord blood serum , and bone marrow cells derived materials . Further, the present invention relates to a composition for metabolic bone diseases , including the undifferentiated mesenchymal stem cells , with the goal multipotential cells and increase cell proliferation and self-renewal capacity Accelerated ;
机译:本发明是为了促进细胞增殖和自我更新能力并增加骨细胞,多能性涉及未分化的间充质干细胞,其制备更具体地涉及一种间充质干细胞及其在培养物中通过培养分离产生的方法含有人脐带血血清的培养基。另外,本发明涉及一种使用该组合物的骨诱导分化的方法,该诱导分化的方法包括将人脐带血清和骨髓细胞来源的物质作为有效成分的间充质干细胞的分化。此外,本发明涉及用于代谢性骨疾病的组合物,其包括未分化的间充质干细胞,其具有目标多能细胞并加速细胞增殖和自我更新能力。

著录项

  • 公开/公告号KR101459814B1

    专利类型

  • 公开/公告日2014-11-14

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110125229

  • 发明设计人 오일환;

    申请日2011-11-28

  • 分类号C12N5/0775;C12N5/02;

  • 国家 KR

  • 入库时间 2022-08-21 15:01:17

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